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Recombinant Anti-CD45 [clone YTH54.12] Antibodies (Standard Size)

Product Name: Recombinant Anti-CD45 [clone YTH54.12] Antibodies (Standard Size)
Size: 200 ug
Catalogue Number: BA-Ab00672-8.1 (Absolute Antibody Products)
Price:
$370.00
Description:

Recombinant monoclonal antibody to CD45. Manufactured using Recombinant Platform with variable regions (i.e. specificity) from the hybridoma YTH54.12. This antibody binds to and immunoprecipiates human CD45. In the original rat IgG2b format it was shown to trigger complement mediated lysis and synergizes with clone YTH24.5 (Ab00671) which binds a different epitope on human CD45.

Notes: Antibody First Published in: Bidon et al. Therapeutic potential of monoclonal antibodies to the leukocyte-common antigen. Synergy and interference in complement-mediated lysis Transplantation. 1985 Nov;40(5):538-44. PMID:2414870 Note on publication: Describes generation and characterization of the synergistic effect of several anti-CD45 antibodies on lysis.
Host Reactivity:

Human

Antigen Name:

CD45

Application:

FC; IP; depletion; IF.

Purity:

Protein A affinity purified.

Species:

Rat IgG2b, kappa

Storage Buffer:

PBS with preservative (0.02% Proclin 300).

Immunogen:

Human T-cells injected into DA rats.

CloneID:

YTH54.12

Spectificity:

This antibody binds human CD45, the leukocyte common antigen, at epitope Q2.

Intended Use:

RUO

Storage Conditions:

Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

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